This strategy is extremely aggressive and requires some genes to work. Watch the world dies and congratulations, you've won.If the whole world have been infected, evolve Unlock Annihilate Gene.Evolve Genetic Reshuffles as needed (if the cure > 75%).If Greenland closes ports before you infect it, restart. ![]() Wait until the whole world infected, if it's not fast enough, evolve Coughing and Sneezing.Evolve Cold Resistance 1,2 Drug Resistance 1,2 and Genetic Hardening 1,2.Evolve Deactivate Modified Genes and Nucleic Acid Neutralisation (we'll need this for the final kill anyway so feel free to max them out).Evolve Air 1, Air 2, Water 1, Water 2, and Extreme Bioaerosol.Evolve Rash, Sweating, and Skin Lesions Note : Don't always devolve the symptoms except if it's too lethal like Necrosis.Genetic Mimic (Absolutely required, in Mega Brutal, they will be curing the plague really fast)Īlright so for the strats, we gonna focus on infecting since Bio Weapon kills very fast, I won using this strategy after 2 times so I guess it's 50-50 to win (I lost because of Greenland).Patho-Stasis (Needed for the final kill).Aquacyte (Needed to infect islands and the most annoying one Greenland).Catalytic Switch (Useful for DNA resources on late game).For genes, I think you could use any but here are my recommendations : This strategy works on Mega Brutal and it's not even that complicated. Then, evolve Unlock Annihilate gene, and after that evolve Genetic Hardening 1 and 2, Insomnia, Paranoia, Seizures, Insanity and Coma (if you have the DNA for it). When the "There are no healthy people in the world" popup appears, evolve Deactivate modified genes 3 and Nucleic Acid Neutralisation 3 if they had not been evolved before.When every country is infected, evolve Coughing to increase infectivity.Keep the plague under control by evolving Deactivate modified genes 2 and Nucleic Acid Neutralisation 2.Evolve Cold Resistance 2 to ensure infectivity in cold countries, especially Greenland.If a plague's lethality is too high or the plague unexpectedly mutates a lethal symptom, evolve Deactivate modified genes 1 (Reduces lethality) and Nucleic Acid Neutralisation 1 (Lethality does not increase for a short time).Evolve in order: Water 1, Air 1, Water 2, Air 2, Cold Resistance 1, Drug Resistance 1, Extreme Bioaerosol and Drug Resistance 2.Evolve Gene Compression 1, 2 and 3 as soon as possible.Start in a country with a hot climate (i.e.Keeping DNA costs to a minimum is generally useful. Patho-stasis: The use of special abilities is essential for Bio-Weapon.Extremophile: A good bonus in all environments is always nice to have.Aquacyte: Island countries are not a big problem with this gene evolved.Genetic Mimic: The cure progresses at a slower rate.ATP Boost: Gene Compression is essential at the very beginning of the game.That's all done, this plague's final stage is pretty easy, but the start and the middle is the difficult part.If you are not done, evolve Genetic ReShuffle 1. Slow the cure with Insomnia, Paranoia, Seizures, Insanity, Paralysis and Coma. If you are cautious and want to make your victory 100%. ![]() When there are no healthy people left in the world, get Unlock Annihilate gene.By now your DNA bar should fills up quickly, if your plague starts to kill a lot again, gets Nucleic Acid Neutralisation 3. ![]() ![]() If your plague starts killing, evolve Nucleic Acid Neutralisation 1, wait until it kills a few more people (100,000), and then evolve Nucleic Acid Neutralisation 2, and after it kills again, evolve Deactivate modified genes 3.
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